Multi-active serum 5 hyaluronic acids

Hydrates and plumps the skin immediately, as well as long term

This serum combines 5 hyaluronic acids of different sizes and shapes (very low, low and high molecular weight with a super hyaluronic acid and a cross-linked hyaluronic acid) representing a total percentage of 0.8% and each providing different benefits for immediate hydration and in the long term and have plumper skin thanks to their ability to retain water molecules. Hyaluronic acid is a reference ingredient in aesthetic medicine. It is naturally present in the skin and plays a role in maintaining the skin's hydration, elasticity and structure.

To support the moisturizing and plumping action of hyaluronic acids, we have also chosen to incorporate other humectants:

• beta glucan, a polysaccharide (sugar molecule) with restorative and healing properties. It's also a great skin-soothing ingredient and even has promising anti-aging benefits.
• polyglutamic acid, a biopolymer forming a film on the surface of the skin. It is also able to attract a lot of water molecules which helps maintain skin hydration.
• a combination of polyglucoronic acid, a precursor of hyaluronic acid, and a yeast extract obtained by fermentation to smooth wrinkles, moisturize and increase the suppleness and resistance of the skin.
• arginine, a moisturizing amino acid that is part of the natural moisturizing factors (NMF) which are compounds naturally present in the skin and play a role in maintaining hydration.

The combination of hyaluronic acid and niacinamide is interesting because the two compounds moisturize the skin according to different modes of action. They complete each other.

Repairs the skin barrier and soothes the skin

This serum also combines two vitamins: vitamin B3 at 5% and pro-vitamin B5 at 2% with an oligopeptide and a complex of ceramides at 2% to fortify the skin barrier and soothe the skin. Vitamin B3, known as niacinamide, increases the synthesis of free fatty acids, cholesterol and ceramides in the skin resulting in a healthier and stronger skin barrier. Pro-vitamin B5, also known as panthenol, provides a soothing sensation by reducing irritation. Thanks to the 'cosmetic drone' technology, the oligopeptide stimulates the production of the components of the stratum corneum to reduce the appearance of irritations and other symptoms on the skin such as dryness, tightness, itching or redness. The ceramide complex also ensures the maintenance of the skin barrier because it is composed of phospholipids, sphingolipids and lecithin, lipids naturally present in the skin whose main function is the formation of the skin barrier.

Corrects the signs of skin aging

This serum also acts on wrinkles, expression lines, skin firmness thanks to the combination of peptides, extracts of centella asiatica and green tea. Among the peptides included in this serum, we find matrixyl 3000% objectified combining palmitoyl Tripeptide-1 with palmitoyl Tetrapeptide-7 to reduce wrinkles and have skin that looks younger and firmer by stimulating the production of collagen. Matrixyl 3000 has been clinically tested. This serum also includes a new matrixyl, matrixyl morphomics (INCI: N-Prolyl Palmitoyl Tripeptide-56 Acetate) with an objectified % as well as argireline (INCI: acetyl hexapeptide-8) to fight this time against wrinkles. expressions like nasolabial folds and frown lines. These synthetic peptides have been combined with two botanical extracts with anti-aging properties: centella asiatica and green tea.

Evens out the complexion

This serum combines two lightening active ingredients: alpha arbutin and licorice extract to even out the complexion, reduce the appearance of dark spots and restore radiance to the skin. Arbutin is one of the best known skin lightening agents. It works by blocking the synthesis of melanin, the skin pigment responsible for dark spots. Arbutin is here coupled with an extract of liquorice, a depigmenting agent with fewer side effects and also having a soothing effect on the skin. Vitamin B3 at 5% also acts as a depigmenting active ingredient by inhibiting the transfer of melanosomes, vesicles transporting melanin, which also makes it possible to fade brown spots.

Hydrates and plumps the skin immediately, as well as long term

Sources:

• Pilot Comparative Study of the Topical Action of a Novel, Crosslinked Resilient Hyaluronic Acid on Skin Hydration and Barrier Function in a Dynamic, Three-Dimensional Human Explant Model, Journal of Drugs in Dermatology, 2016 April
• Research Article Acetylated Hyaluronic Acid: Enhanced Bioavailability and Biological Studies, BioMed Research International 2014
• The anti-wrinkle properties of sodium acetylated hyaluronate, Journal of Cosmetic Dermatology, 2021
• Skin health promotion effects of natural beta-glucan derived from cereals and microorganisms: a review, Phytotherapy Research, 2014
• Poly-γ-glutamic acid: production, properties and applications, Microbioloy, Volume 161, Issue 1, 2015

Repairs the skin barrier and soothes the skin

Sources:

• Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier, Journal of Dermatology, 2000
• Nicotinic acid/niacinamide and the skin, Journal of Cosmetic Dermatology, 2004
• Topical use of dexpanthenol: a 70th anniversary article, Journal of dermatology Treatment, 2017
• The role of epidermal sphingolipids in dermatologic diseases, Lipids in Health Disease, 2016

Corrects the signs of skin aging

Sources:

• The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study, American Journal of clinical Dermatology, 2013
• Evaluation of the anti-wrinkle efficacy of cosmetic formulations with an anti-aging peptide, Ars Pharmaceutica, 2009
• Skin rejuvenation using cosmetic products containing growth factors, cytokines, and matrikines: a review of the literature, Clinical, Cosmetic ang Investigational of Dermatology. 2016
• Green tea in dermatology – myths and facts, Journal Der Deutschen Dermatologischen Gesellschaft, Volume 13 (8)– Aug 1, 2015
• Protective Mechanisms of Green Tea Polyphenols in Skin, Oxidative Medicine and Cellular Longevity. 2012
• A new matrikine-derived peptide up-regulates longevity genes for improving extracellular matrix architecture and connections of dermal cell with its matrix, International Journal of Cosmetic Science, 2020

Evens out the complexion

Sources:

• Arbutin: mechanism of its depigmenting action in human melanocyte culture, Journal of Pharmacology and Experimental Therapeutics February 1996
• Natural options for the management of hyperpigmentation, Journal of the European Academy of Dermatology and Venereology, 2011
• Efficacy of licorice extract in the treatment of melasma: A randomized, double-blind, placebo-controlled clinical trial, Journal of dermatology and cosmetics, 2016
• Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin, International Journal of cosmetic science, 2004