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The mechanisms of action of LEDs and lasers for stimulating hair bulbs involve several cellular and molecular processes documented in scientific literature:
• Light absorption by chromophores: in hair follicle cells, mitochondrial cytochrome c oxidase is associated, in scientific literature, with absorption of light at 650 nm, leading to increased enzymatic activity and higher ATP production.
• Cellular energy: this increase in ATP is associated, in scientific literature, with supporting cellular metabolic processes, potentially helping maintain follicles in the anagen phase (growth phase).
• Growth factors: photobiomodulation at 650 nm is associated, in scientific literature, with stimulating the release of growth factors such as VEGF and FGF, involved in cell proliferation and survival within hair follicles.
• Microcirculation: these mechanisms are associated, in scientific literature, with improved microcirculation around hair follicles, contributing to better nutrient supply.
• Scalp environment: photobiomodulation at 650 nm is associated, in scientific literature, with modulating skin inflammation mediators, potentially contributing to a favorable environment for hair follicles.
The effectiveness of photobiomodulation depends on several factors: wavelength, power, duration, and session frequency. The NOOĀNCE helmet combines LEDs and lasers at 650 nm to offer even scalp coverage and targeted penetration.
After regular use according to recommendations, many users may observe visible improvement in hair growth and reduced hair loss, as confirmed by the independent GREDECO clinical study.
Scientific studies
Scientific literature
The effectiveness of photobiomodulation for hair health is supported by a growing body of scientific research. Available data in the literature indicate that results appear gradually, with regular use over several months, following the protocol used in the GREDECO clinical study conducted on the NOOĀNCE helmet (21 volunteers, 6 months, under dermatological supervision by Dr Sylvie Boisnic).
The tolerance of the NOOĀNCE helmet was evaluated throughout this study: dermatological tolerance was excellent over the entire period. Some users may feel slight warmth or tingling sensations at the start of use, without adverse effects.
The NOOĀNCE helmet is a cosmetic device designed for people wishing to care for the quality and density of their hair. Results may vary depending on individuals and hair profile. If in doubt about your personal situation, we recommend consulting a dermatologist.
The scientific research below documents the mechanisms and effectiveness of hair photobiomodulation on which NOOĀNCE technology is based:
- Study on the effectiveness of LEDs and lasers on hair growth
- Role of Low-Level Light Therapy (LLLT) in Androgenetic Alopecia (2021)
- Comparison of low-level light therapy in the treatment of female pattern hair loss (2020)
- Photobiomodulation for the management of hair loss (2020)
- Energy-based Devices for Hair Loss (2021)
- Factors influencing the effect of photobiomodulation in the treatment of androgenetic alopecia: A systematic review and analyses of summary-level data (2020)
- Low-level laser therapy for the treatment of androgenic alopecia: a review (2018)
- Low-Level Laser (Light) Therapy (LLLT) for Treatment of Hair Loss 2015
- Effects of LEDs in dermatology
- Effect of wavelength and beam width on penetration in light-tissue interaction using numerical methods